Effects of vitamins on diabetics patients || is vitamin b12 good for diabetics ?- pharmacyteach.com

 Vitamin and diabetes

 

Vitamins are important components of nutrition for human health. 13 vitamins are required for good health, out of them four are fat-soluble ( A, D, E, and K ) other all vitamins are water-soluble. The human body can synthesize some vitamins such as vitamin D synthesis from steroids and vitamin K from normal flora.

All these vitamins have important functions in different parts of the body and their deficiency can cause specific syndromes or diseases. The following table has mentioned the function and deficiency syndrome of various vitamins.

 

In This article we discussed which vitamin is beneficial for diabetics and which causes complications with diabetes this is the largely asked question, is vitamins supplement are can be taken by diabetic patients? . Are vitamins cause any complications with diabetes?

 

As we know that diabetes is a condition in which the body has high blood glucose levels in blood circulation. Diabetes has two types,

 

•    type 1 diabetes, 
•     type 2 diabetes.

 

In type 2 diabetes body shows resistance against the insulin produced by the pancreas. As a result cells unable to uptake glucose from the bloodstream and increase the glucose level in the blood.

 

Vitamins and minerals are beneficial for diabetics:-

 

   Still, there is no complete cure for type 2 diabetes but some prevention can have beneficial effects on diabetes such as weight loss, exercise, proper diets, and diabetics medications. There are some vitamins and minerals that can help to maintain diabetes.

 

 

Vitamin A for diabetes:-

 

Vitamin A has fat-soluble vitamins and is a most necessary nutritional component that has a fascinating function in our body. Vitamin A consists of different compounds but Retinol has the most active form, which is the Esterified form of long-chain fatty acid found in animal tissue. Vitamin A performs a serious function in our body such that it is necessary for the maintenance of normal vision, Act as an anti-oxidant, and is involved in lipid metabolism. Specific retinol-binding protein (RBP )  is a type of protein synthesis by the liver Which serves as a career for retinol to Peripheral tissue where it releases retinol and RBP has to recycle back into the bloodstream. RBP acts as an adipokine and Affects insulin sensitivity. In adult diabetic patients retinol serum concentration is normal but Old Age type 2 diabetic subjects have lower plasma concentrations of retinol.

 

2 . Vitamin B for diabetes:-

 

There are several research study shows that vitamin B12 deficiency occurred in Type 2 diabetes mellitus patients. Most vitamin B12 deficiency is associated with Metformin which is used as a first-line treatment for lower glucose levels in type 2 diabetic patients. Metformin cause Vitamin B12 deficiency in those who Use it for the long term (about 4 to 5 years) and on high doses i.e. greater than 2g/day.

Vitamin B12 deficiency is not only associated with Metformin-taking patients. it has also been observed in the non- Metformin taking diabetic patients whose occurrence ratio is greater with Metformin therefore; it is suggested to take Vitamin B12 supplements in such patients. Vitamin B12 deficiency risk is increased with age and use and dose of Metformin.

 

The vitamin 12 deficiency by the metformin in Type 2 diabetes can be by ;

Decrease or inhibit the absorption of vitamin B 12. Overgrowth of bacterial stimulation by alteration in the motility of the small bowl.

On the other hand, Type 2 diabetes mellitus vitamin B12  can cause hyper-homocysteinemia because Vitamin B 12 and folic acid deficiency are associated with oxidative stress And diabetic Mellitus has an oxidative stress disease. Peripheral neuropathy in Type 2 Diabetes Mellitus is one of the most repeated complications associated with hyper-homocysteinemia.

 So it is concluded that vitamin B 12 sublimation should be taken by type 2 diabetes mellitus patients, especially metformin users. Otherwise, vitamin B 12 deficiency cause hyper-homocysteinemia  Which can lead to peripheral, neuropathy and other complication.

3 . Vitamin C:-

 

Some research study show date vitamin C has useful for type 2 diabetic patients. Ascorbic acid (vitamin C ) has performed an important role in the body, such as at act as a cofactor for different Reactions, as an antioxidant, required for Carnitine synthesis and Iron absorption, and is  Immune system stimulation. In case study shows that vitamin C&E plasma concentration has decreased with diabetes.

 

 The research team of Deakin  University in  Victoria publish a study that shows that  Supplement vitamin C can benefit effect for reducing blood sugar levels. And also maintain BP in people suffering from diabetes. If you consume 500 milligrams of vitamin C two times a day. It will help you decrease blood sugar levels the Whole day and control the sudden increase of blood sugar after meals.

 

The research study shows that vitamin C helps reduce blood sugar through its antioxidant property Which counteracts free radicals Highly found in diabetes. Vitamin C has water-soluble vitamins and  Roummages free radicals and Inhibits the entry of these radicals into the LDL cholesterol. Therefore vitamin C also has a positive on heart Health.

 

4. Vitamin D:-

Vitamin D deficiency develops a high risk of diabetes. Therefore, vitamin D supplementation must be taken by diabetic subjects. We can obtain vitamin D from various sources, for example, sunlight, food, and supplementation can beneficial for regulating insulin levels. It is shown that vitamin D supplements help lower blood sugar levels in people who suffer from type 2 diabetes Mellitus.

 

From where we can obtain vitamin D?

 

 The major source of vitamin D has our skin. Human skin is capable to create vitamin D when exposed to direct sunlight. Show everybody should be exposed to direct sunlight for 15 to 20 minutes  Every day as beneficial for a person's health. Some food also contains a small amount of vitamin D, like oily fish, egg yolk, etc. But most foods do not contain such a good quantity of vitamin D therefore a lot of people take vitamin D supplements.

 

 Research conducted on vitamin D and diabetes subjects.

 Diabetics patients should check their level Of vitamin D because many people have a low concentration of vitamin D with diabetes. And it has been known to help regulate diabetes. A recent review of a research study explored that the Use of vitamin D supplementation can control blood sugar levels in adults with type 2 diabetes. But fasting sugar level has not been affected. The greater effect will occur by taking vitamin D supplements for longer than 2 weeks at a dose of. 1000 ul/day. His only belief is that Vitamin D plays an important role and managing diabetes But still, research has continued for more details.

 

 

 Can Vitamin D improve insulin function. ?

vitamin D is also involved in directly improving insulin sensitivity by insulin receptor stimulation And activation of PPAR-delta. The function of the pancreatic cell can also be facilitated by the exposure of 1,25 di hydroxy vitamin D to its specific receptor on the beta cell.

 

5. Chromium:-

A study shirt date chromium supplementation has been helpful and decreasing insulin resistance and controlling glycemic levels. Insufficient chromium maybe leads to diabetes but kidney patient should be used chromium with caution. Chromium can damage kidneys and get the worse disease. Dietary chromium absorption has decreased with the age. chromium. Chromium picolinate is a form of chromium that is most effective in lowering blood sugar levels.