Complete classification of GIT drugs ||pharmacyteach.com

Classification of GIT drugs

Introduction

When it comes to medications, there's a lot of acronyms and abbreviations to keep track of. GIT drugs are no exception. So what do they stand for?

GIT drugs refers to gastrointestinal tract drugs. This classification of drugs helps us target medication to the parts of the body that need it most.

In this article, we'll provide a complete breakdown of GIT drugs and their uses, side effects, and more.

What Are GIT Drugs?

GIT drugs are medications that are used to treat gastrointestinal problems. These drugs work by altering the way the digestive system works.

There are a variety of different GIT drugs available, and they are used to treat a range of different problems. Some of the most common GIT drugs include antacids, proton pump inhibitors, and H2 blockers.

GIT drugs can cause a variety of side effects, including nausea, vomiting, and diarrhea. It is important to speak to your doctor if you are experiencing any side effects while taking GIT drugs.

What Are the Uses of GIT Drugs?

You might be wondering what GIT drugs are used for. These medications are typically prescribed to treat conditions like diarrhea, nausea, and vomiting. They work by reducing the amount of gastric acid in the stomach, which can help to improve symptoms.

There are a variety of different GIT drugs available, and each one has a slightly different chemical makeup. This means that they can all have different side effects. It's important to discuss all the potential risks and benefits with your doctor before starting treatment.

What Are the Side Effects of GIT Drugs?

All medications come with the risk of side effects, and GIT drugs are no exception. Some of the most common side effects of GIT drugs include:

• Nausea

• Vomiting

• Constipation

• Diarrhea

• Headache

• Dizziness

• Loss of appetite

• Fatigue

If you experience any of these side effects, be sure to speak to your doctor.

What Are the Contraindications of GIT Drugs?

When you're taking GIT drugs, it's important to be aware of the contraindications. This means knowing the drugs that shouldn't be taken with your medication and being aware of any potential interactions.

Some common contraindications for GIT drugs are listed below. If you're taking any of these medications, be sure to speak with your doctor before starting a course of GIT drugs.

How to Take GIT Drugs?

Now that you have a general understanding of GIT drugs, let's talk about how to take them. As we mentioned earlier, there are a few different ways to take GIT drugs, depending on the type of drug you're taking.

For example, if you're taking a pill, you can usually just swallow it with a glass of water. But if you're taking a drug that needs to be dissolved in water first, like Imodium A-D, then you'll need to mix it with water and drink it down.

And if you're taking an injectable drug like Depakote, your doctor will show you how to give yourself the injection. It can seem daunting at first, but with a little practice, it's not too bad.

Conclusion

There are a variety of GIT drugs on the market, each with its own unique set of uses and side effects. Knowing which drug is best for your specific needs is essential to getting the most out of your medication.

Always be sure to consult with your doctor before starting any new medication, and be sure to report any and all side effects you experience while taking GIT drugs.

 Nonspecific Antidiarrhoeal Drugs

Absorbents

• Ispaghula,

• Psyllium,

• Methylcellulose

Antisecretory drugs

• Sulfasalazine,

• Mesalazine,

• Olsalazine,

• Balsalazide,

• Bismuth subsalicylate,

• Atropine,

• Octreotide,

• Racecadotril

Antimotility drugs (opioids)

• Codeine,

• Diphenoxylate atropine,

• Loperamide

Antiemetics

Anticholinergics:

• Hyoscine,

• Dicyclomine

H1  antihistaminics:

• Promethazine,

• Diphenhydramine,

• Dimenhydrinate,

• Cyclizine,

• Doxylamine,

• Meclozine,

• Cinnarizine

 Neuroleptics:

• Chlorpromazine,

• Prochlorperazine

• Haloperidol, etc.

Prokinetic drugs:

• Metoclopramide,

• Domperidone,

• Cisapride,

• Mosapride,

• Itopride,

• Tegaserod

5-HT3  antagonists:

• Ondansetron,

• Granisetron

Adjuvant antiemetics:

• Dexamethasone,

• Benzodiazepines,

• Cannabinoids   (Nabilone,  Dronabinol)

Drugs for Gastroesophageal Reflux Disease (GERD)

Inhibitors/neutralizers of gastric acid secretion

Proton pump inhibitors (PPIs):

• Omeprazole,

• Pantoprazole and others.

H2 blockers:

• Ranitidine,

• Famotidine

Antacids:

• Magnesium hydroxide,

• Aluminium  hydroxide

Barrier agent

• Sodium alginate

Prokinetic drugs:

(Enhance LES tone and promote  gastric emptying)

• Cisapride,

• Mosapride,

• Metoclopramide

 Drugs for Peptic Ulcer

Gastric acid secretion inhibitors

H2 antihistamines: 

• Cimetidine,

• Ranitidine,

• Famotidine,

• Roxatidine

Proton pump inhibitors:

• Omeprazole,

• Esomeprazole,

• Lansoprazole,

• Pantoprazole,

• S (-) Pantoprazole,

• Rabeprazole,

• Dexrabeprazole.

Anticholinergics:

• Pirenzepine,

• Propantheline,

• Oxyphenonium

Prostaglandin analogs:

• Misoprostol

Gastric acid neutralizers (Antacids)

Systemic:

• Sodium bicarbonate,

• Sod. citrate

Nonsystemic: 

• Magnesium hydroxide

• Mag. trisilicate,

• Aluminium hydroxide gel,

• Magaldrate,

• Calcium carbonate

Ulcer protectives

• Sucralfate,

• Colloidal bismuth subcitrate (CBS)

 Anti-H. pylori drugs

• Amoxicillin,

• Clarithromycin,

• Metronidazole,

• Tinidazole,

• Tetracycline

Laxatives

(Purgatives, Cathartics)

Bulk-forming agents

Dietary fiber:

• Bran,

• Psyllium (Plantago)

• Ispaghula,

• Methylcellulose

Stool softener

• Docusates (DOSS),

• Liquid paraffin

 

Stimulant purgatives

Diphenylmethanes

• Phenolphthalein,

• Bisacodyl,

• Sodium picosulfate

Anthraquinones (Emodins)

• Senna,

• Cascara sagrada

 5-HT4 agonist

• Tegaserod

Fixed oil

• Castor oil

Osmotic purgatives

Magnesium salts:

• sulfate, hydroxide

Sodium salts:

• sulfate, phosphate

Sod. pot. tartrate

Lactulose

Nonspecific Antidiarrhoeal Drugs

                    Absorbents

1. Ispaghula:-

                            Ispaghula is used as a natural medicine for the treatment of constipation and as well as for the softening of stool in normal life.

How to take ispaghula?

• Ispaghula is available 8n the form of granules in sachets you should take ispaghula mixed into a full glass of juice or water. Allow the ispaghula to swell for better results.

• Don’t take so much, large amounts can be dangerous.

• Adults can take the once and twice-a-day dose of ispaghula.

• For any complications consult your doctor as soon as possible.

2. Psyllium :-

                   Psyllium and ispaghula are the same things used as a laxative.

• They absorb water in the intestine as a result increase the bulk of stool which is easy to pass out by the intestine.

• It can be used for mild to severe constipation.

3. Methylcellulose:-

Methyl cellulose is a derivative of cellulose. it is used as a thickener and bulk-forming laxative.

• It is used for the treatment of constipation taken by mouth with sufficient water.

• It is also used for the treatment of dry eyes.